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2-Hydroxyestrone

Meaning

2-Hydroxyestrone is a specific metabolite of the primary estrogen hormone, Estradiol (E2), created during the body’s Phase I liver detoxification process. It is generally considered a “good” or protective estrogen metabolite due to its lower proliferative activity on estrogen-sensitive tissues compared to other derivatives. Clinical assessment of this compound, alongside others, is crucial for evaluating overall estrogen metabolism pathways and informing personalized hormonal balance strategies. This compound’s ratio to other metabolites provides valuable insight into long-term hormonal health and disease risk.